Scientists have discovered the key features of immune B cells which make them successful at targeting tumours – including when cancer has spread to a different part of the body. Published in Nature Immunology, the researchers have developed a computational tool to identify these anti-cancer immune cells which could lead to improved, personalised immunotherapies. Most […]
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Pancreatic cancer cells can change their ‘diet’ to keep growing, by switching from the sugar glucose to a back-up fuel called uridine, new research reveals. The findings suggest that blocking the availability of uridine using new drugs could become a new treatment strategy for the most common and aggressive form of pancreatic cancer. The researchers […]
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Cancer cells can shrink or super-size themselves to survive drug treatment or other challenges within their environment, researchers have discovered. Scientists at The Institute of Cancer Research, London, combined biochemical profiling technologies with mathematical analyses to reveal how genetic changes lead to differences in the size of cancer cells – and how these changes could […]
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New intestinal cancer treatment approach identified by the Medical University of Vienna. A MedUni Vienna study group has identified a previously unknown mechanism involved in the development of intestinal cancer: The bacterial microbiome activates the so-called immune checkpoint Ido1 in Paneth cells, a special cell that is only found in the gastrointestinal tract, thereby preventing […]
Researchers from the University of East Anglia have helped to carry out the first comprehensive survey of viruses found within different types of cancer. An international team systematically investigated the DNA found within more than 2,600 tumour samples from patients with 38 different types of cancer. They discovered traces of viruses in 13 per cent […]
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“Sometimes chromosomes can break and get reattached to a different one in an unusual way. This results in a fusion between one gene and another which makes a new gene, called a gene fusion. Cancer cells often have gene fusions which happen because the DNA in cancer cells is really messed up such as the […]