chromatin Archives - The Hippocratic Post

Chromatin openness sheds new light on prostate cancer plasticity

Posted on June 3, 2024 by Hippocratic Post

Treatment resistance caused by cancer cell plasticity constitutes a major challenge in the treatment of prostate cancer. Published in Nucleic Acids Research, a recent study from the University of Eastern Finland Institute of Biomedicine suggests that the SIX2 protein may be a possible factor underlying increased plasticity of prostate cancer cells and treatment resistance. Prostate […]

Genetic Variation Influences Gene Regulatory Actions

Posted on January 22, 2024 by Hippocratic Post

Genetic variation determines the actions of gene regulatory factors: A recent study from the University of Eastern Finland shows that genetic variation determines chromatin accessibility and the binding of transcription factors. Chromatin consists of DNA and proteins attached to it. The density of this packaging is regulated by transcription factors, and DNA accessibility is required […]