A common human gene mutation combination – found in around 5% of the UK’s black population as well as millions of people worldwide with recent African ancestry – has been linked to a number of health conditions and poor health outcomes in new research. The breakthrough study, led by researchers at the University of Glasgow […]
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Genetic variation determines the actions of gene regulatory factors: A recent study from the University of Eastern Finland shows that genetic variation determines chromatin accessibility and the binding of transcription factors. Chromatin consists of DNA and proteins attached to it. The density of this packaging is regulated by transcription factors, and DNA accessibility is required […]
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Fruit flies and humans don’t just share a love of fruit in the warm summer months. We also share key genetic features, which scientists have been able to take advantage of in new research to better understand how diet affects health. The latest study, which is led by the University of Glasgow and published in […]
How genetics, diet and gut health influence Alzheimer’s risk: Scientists at the University of East Anglia and the Quadram Institute are launching a new study to investigate how our genes, diet and microbiome influence the risk of dementia. Recent research has linked gut health to Alzheimer’s disease. And dietary compounds found in foods including fruits […]
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Scientists Unveil the Mechanism Behind Intracellular Connection: Mitofusin 2 is the Lock and Key. Researchers at IRB Barcelona, the University of Barcelona (UB), VIMM, and the University of Padua unveil the key role of Mitofusin 2 cellular makeup in interconnecting organelles within cells. As essential structures with specialized functions, these organelles rely on intricate connections […]
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Testing a population for multiple genes at once will always be limited in its ability to accurately predict disease risk, experts are warning. An analysis published in the British Medical Journal concludes that population-wide ‘polygenic scoring’ is inherently limited because many cases of disease occur among people who do not have high polygenic scores and […]
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A major new study in the journal Nature reveals a ‘traffic light’ mechanism controlling genetic activity within cells – a system which could potentially be targeted by cancer drugs already in development. The research describes how ‘epigenetic’ changes to the structure of DNA can act as a stop-go signal in determining whether a gene should […]
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Visual damage refers to any injury or damage that affects a person’s visual system. This includes the eyes and the parts of the brain that process visual information. It is considered visual damage if there is any injury to the lens, cornea, optic nerve, retina, or other parts of the eye, as well as damage […]
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Genetic background has an effect on the metabolism of the essential polyunsaturated fatty acids alpha-linolenic acid and linoleic acid, a recent study from the University of Eastern Finland shows. Supplementing the diet with camelina oil rich in alpha-linolenic acid, or with sunflower oil rich in linoleic acid altered the concentrations of the metabolites of these […]
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UK participants needed to help discover genes behind stammering. More than 1500 adults and children from the United Kingdom are being recruited for an international study aiming to discover the genes that cause stammering. The largest study of its kind hopes to provide greater insight into why some people are more likely to develop a […]