Children in England and Wales with the most common paediatric brain tumour now have access to new treatment

paediatric

• The National Institute for Health and Care Excellence (NICE) has recommended the combination therapy of dabrafenib (Finlee®) and trametinib (Spexotras®) for the treatment of paediatric patients with low-grade glioma (LGG) and high-grade glioma (HGG) who have a BRAF V600E mutation. • BRAF V600E mutation is present in 15-20%2 of LGGs and in 5-10%3 of […]

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Enhancing Brain Tumor Imaging Diagnostics

Brain Tumour Imaging

Enhancing Brain Tumor Imaging Diagnostics: Diffuse gliomas are malignant brain tumors and cannot be optimally examined by conventional imaging using MRI. Amino acid PET can better visualize the activity and spread of gliomas. An international research group (RANO Group) led by MedUni Vienna and LMU Munich has now established the first international criteria for standardized […]

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First Patient in Historic First-in-Human Clinical Trial for Glioblastoma

first

The Ivy Brain Tumor Center at Barrow Neurological Institute, the largest early-phase drug development program for brain cancer in the world, has announced the dosing of its first patient in a first-in-human Phase 0 clinical trial of sonodynamic therapy (SDT), a non invasive drug-device combination developed by SonALAsense in collaboration with Insightec. This historic study aims to develop […]

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