NorUDCA (24-nor-ursodeoxycholic acid) is a chemically modified bile acid that has already shown promising results in the treatment of liver diseases such as primary sclerosing cholangitis (PSC) and is being tested in clinical studies. As PSC is often associated and potentially causally linked with chronic inflammatory bowel disease, a MedUni Vienna research team, jointly led […]
Approximately half of patients with advanced liver disease have varicose veins in the oesophagus and stomach, and a more than a fifth of them experience bleeding from these varices into the digestive tract. This is a life-threatening complication that contributes significantly to the still high mortality rate in cirrhosis. An international research team led by […]
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The government has reneged on its pledge to offer liver scans in the newly announced Community Diagnostic Centres in England, warns the UK’s leading liver health charity. The British Liver Trust raised concerns following an official correction by Government, after the Minister had previously made the commitment in writing. The original announcement to roll out […]
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New study reveals way to predict side-effect risk from common immune suppressant medication: A major new study has found a method to identify people who may experience blood, kidney, or liver related side-effects from methotrexate, the most commonly used immune-suppressing medicine with 1.3 million users in the UK. The method, known as ‘risk stratification’, predicts […]
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Tick tock – the liver controls the circadian clock: University of Queensland-led research has revealed liver cells influence the body’s internal circadian clock, which was previously believed to be solely controlled by the brain. Associate Professor Frédéric Gachon from UQ’s Institute for Molecular Bioscience and Dr Serge Luquet from Université Paris Cité/CNRS in France and […]
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Some obesity-related genes protect people from type 2 diabetes, while others increase risk: New research presented today at the Diabetes UK Professional Conference 2023 and funded by Diabetes UK has pinpointed five unique combinations of genes that either help protect people living with obesity and overweight from developing type 2 diabetes or increase their risk. […]
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Struggling with hangxiety? Dr Luke Powles, Clinical Director at Bupa Health Clinics examines the physical effect of alcohol consumption in the immediate, short and long-term, and in each instance what are the signs to look out for? Over the last 90 days, Google Trends shows there’s been a huge 4,550% increase in searches for ‘recommended […]
In a recent study, an interdisciplinary research team from MedUni Vienna showed that functional magnetic resonance imaging (fMRI) can be used as a non-invasive method for predicting complications in chronic liver disease. The scientists combined a simple risk stratification system developed at MedUni Vienna – the functional liver imaging score (FLIS) – with splenic diameter. […]
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Diseased male livers undergo sex-change: The livers of men diagnosed with hepatic diseases change sex as part of a potential self-protective mechanism, according to University of Queensland research. Institute for Molecular Bioscience (IMB) lead researcher, Associate Professor Frederic Gachon said the surprise discovery was made during an investigation into why disruption of the body’s circadian clock is associated with […]
A University of Queensland start-up company, developing a potential new treatment for obesity-related liver disease, has secured a seed investment of $1.3 million from IP Group, a UK-based intellectual property business. Jetra Therapeutics Pty Ltd is developing a treatment with the potential to reverse liver damage caused by Non-alcoholic Fatty Liver Disease (NAFLD) and Non-alcoholic […]
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