NorUDCA (24-nor-ursodeoxycholic acid) is a chemically modified bile acid that has already shown promising results in the treatment of liver diseases such as primary sclerosing cholangitis (PSC) and is being tested in clinical studies. As PSC is often associated and potentially causally linked with chronic inflammatory bowel disease, a MedUni Vienna research team, jointly led […]
New research from the University of Aberdeen could lead to the development of medication for disease that affects 1 in 4 people worldwide but is currently untreatable. The study, which is published in Cell Metabolism was carried out by an international team of scientists, led by Professor Lora Heisler from the University of Aberdeen Rowett […]
Read More… from Important breakthrough in treating liver disease
Approximately half of patients with advanced liver disease have varicose veins in the oesophagus and stomach, and a more than a fifth of them experience bleeding from these varices into the digestive tract. This is a life-threatening complication that contributes significantly to the still high mortality rate in cirrhosis. An international research team led by […]
Read More… from Risk assessment after severe complication of liver cirrhosis improved
Alcohol-related liver disease is among the most common causes of morbidity and mortality worldwide. Due to an incomplete understanding of the factors contributing to disease development, liver transplantation is still the only available cure. A team led by Tim Hendrikx from MedUni Vienna’s Department of Laboratory Medicine has now uncovered a new mechanism that plays […]
Even after chronic hepatitis C has been cured, portal hypertension remains the major factor driving the development of complications in advanced liver disease. In cooperation with researchers from Spain, a research team led by Georg Semmler and Mattias Mandorfer from the Division of Gastroenterology and Hepatology at MedUni Vienna’s Department of Medicine III showed that […]
Read More… from Hepatitis C: Accurate prediction following non-invasive testing
If liver tissue has to be removed due to cancer or another liver disease, the organ usually regenerates quickly, soon becoming fully functional once again. Medical science has not yet completely understood the complex processes that enable tissue recovery following resection. Now, for the first time, a MedUni Vienna research team has discovered the vital […]
Death from alcohol-related liver disease could be prevented with early diagnosis and intervention, says new study: Patients dying of alcohol-related liver disease had frequent interactions with secondary care services prior to their death, and a new study has found that these opportunities to address their high-risk drinking behavior could have been missed. The research found that […]
Read More… from Early diagnosis of alcohol-related liver disease could prevent death
In a recent study, an interdisciplinary research team from MedUni Vienna showed that functional magnetic resonance imaging (fMRI) can be used as a non-invasive method for predicting complications in chronic liver disease. The scientists combined a simple risk stratification system developed at MedUni Vienna – the functional liver imaging score (FLIS) – with splenic diameter. […]
Read More… from Liver disease: New non-invasive method of risk assessment
Exercise supports the treatment of non-alcoholic fatty liver disease by impacting on several metabolic pathways in the body, a new study from the University of Eastern Finland shows. Regular HIIT exercise over a period of 12 weeks significantly decreased the study participants’ fasting glucose and waist circumference, and improved their maximum oxygen consumption rate and […]
Read More… from Study sheds light on the benefits of exercise in fatty liver disease
Diseased male livers undergo sex-change: The livers of men diagnosed with hepatic diseases change sex as part of a potential self-protective mechanism, according to University of Queensland research. Institute for Molecular Bioscience (IMB) lead researcher, Associate Professor Frederic Gachon said the surprise discovery was made during an investigation into why disruption of the body’s circadian clock is associated with […]