New combination immunotherapy against breast cancer

New combination

A new combination therapy against cancer has been investigated by a research team at the Medical University of Vienna led by Maria Sibilia. This therapy employs systemic administration of the tissue hormone interferon-I combined with local application of Imiquimod. This combination showed promising results in topically accessible tumors like melanoma and breast cancer models: The […]

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Study exposes risks of skin cancer in elite swimmers

Only a small proportion of elite swimmers regularly checked their skin for signs of cancer despite being at increased risk, according to University of Queensland research. Forty-four South East Queensland athletes and 23 support staff took part in a pilot study conducted by the Frazer Institute’s Professor H. Peter Soyer and Professor Monika Janda from […]

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Melanoma Death Rate Higher in Patients with Darker Skin

darker

A podcast series explores the disproportionately high mortality rate for people with darker skin diagnosed with melanoma skin cancer. Melanoma is the deadliest form of skin cancer and the rate has increased by about one-third over the last decade in the UK. Researchers have projected a record high of 20,800 cases this year with an […]

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28% of UK adults are using sunbeds as skin cancer rates rise

sunbeds

New data released today by the charity Melanoma Focus has found that over a quarter (28%) of adults in the UK say they use sunbeds, rising to 43% of 18-25 year olds. The research shows that sunbed use is alarmingly high across the country but that Belfast is the ‘sunbed capital of the UK’ with […]

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The secret life of CD4+ T cells: from helpers to melanoma fighters

CD4+

The secret life of CD4+ T cells: from helpers to melanoma fighters: Researchers have revealed unprecedented insights into CD4+ T cells, a type of immune cell, which show promise for immunotherapies against melanoma, the most severe form of skin cancer. In the study led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) […]

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Risk Model Predicts Response and Survival in Metastatic Cancer Patients

Risk model

Risk model based on routine blood work predicts treatment response and survival of metastatic cancer patients treated with immune checkpoint inhibitors. A risk model developed by researchers can help to identify cancer patients who could benefit from immune checkpoint inhibitors, ICIs. Published in BMC Cancer, the study was conducted at the University of Eastern Finland […]

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Potential genetic screening for aggressive melanoma

aggressive melanoma

Potential genetic screening for aggressive melanoma: Researchers from The University of Queensland and The Alfred hospital in Melbourne have identified gene variants which may contribute to people being at higher risk for nodular melanoma. Dr Mitchell Stark from UQ’s Frazer Institute said nodular melanoma only accounts for around 14 per cent of invasive melanoma cases, […]

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Sunscreen cost increasing risk of skin cancer

sunscreen

Melanoma is a deadly, but largely preventable, form of skin cancer. Wearing sunscreen is one of the most effective ways to protect against it, but new data released today by the charity Melanoma Focus has found that half (50%) of people in the UK think sunscreen is too expensive and 10% don’t use it at […]

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Fewer cases of melanoma among people with atopy

people

Fewer cases of melanoma were observed in people with a history of atopic diseases, such as allergic asthma or rhinitis, than in nonatopic people. The risk of melanoma in people with atopy was up to 50% lower than in the control group. In addition, people with atopy had a considerably lower overall risk of skin […]

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Cancer cells shrink or super-size to survive

cells

Cancer cells can shrink or super-size themselves to survive drug treatment or other challenges within their environment, researchers have discovered. Scientists at The Institute of Cancer Research, London, combined biochemical profiling technologies with mathematical analyses to reveal how genetic changes lead to differences in the size of cancer cells – and how these changes could […]

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