Aggressive cancers could be treated with immunotherapies that direct the immune system to kill cancer cells with specific drug resistance-causing mutations, a major new study suggests. Drug resistance mutations which restore activity of the BRCA1 or BRCA2 genes as a way of avoiding the effects of drug treatment could leave tumours vulnerable to the effects […]
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Precision drugs could unmask cancers to the immune system and boost the effects of immunotherapy – NHS-approved PARP inhibitor therapy found to boost the body’s immune response – Drugs could be used to increase number of patients who respond to immunotherapies – Treatment developed for ovarian and breast cancers could also work in some lung […]
Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for the treatment of cancer. Their study, published in Nature, uncovered a brand new protein complex in cells that shields broken DNA ends and controls the way in which it is repaired. The new complex pushes […]
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