Arginine Depletion as a Starting Point for Potential Treatments

A group from the MedUni Vienna has identified a role for the endogenous amino acid arginine in the growth of osteoclasts in rheumatoid arthritis. Restricting the amount of available arginine significantly restricts excessive formation of these harmful, disease promoting cells. These findings, which were recently published in the leading journal Nature Communications, could form the […]

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Calming immune cells

Scientists have found a way to calm immune cells, reducing inflammation which can lead to diseases including rheumatoid arthritis and sepsis. In a study published this week in the journal Nature Communications, researchers at Imperial College London, Queen Mary University of London and Ergon Pharmaceuticals, explain how blocking a single enzyme enabled them to reprogram […]

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Then and now – your bones

Today three million woman in the UK are diagnosed with so-called brittle bone disease, but back in the 1960s, it was poorly understood. Old ladies were told they had widow’s hump which was considered a normal part of ageing. Few hospital consultants had a good knowledge of osteoporosis and a recognised definition was not produced […]

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